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Acute myelogenous leukemia (AML) is also known by several
other names, including acute myeloblastic
leukemia, acute myelocytic leukemia and acute
nonlymphocytic leukemia. AML is not inherited or
contagious. It develops when there is a
defect in the immature cells in the bone marrow.
Normally, bone marrow cells mature into several
different types of blood cells. Acute
myelogenous leukemia affects the young blood cells
(called blasts) that develop into a type of white
blood cell (called granulocytes). The main
function of granulocytes is to destroy bacteria.
The blasts, which do not mature and become too
numerous, remain in the bone marrow and blood.
Acute leukemia can occur over a short period of
days to weeks. Chromosome abnormalities (extra
chromosomes and structural changes in the
chromosome material) are present in the majority
of ALL (acute lymphocytic leukemia) patients.
Causes
Like Acute lymphocytic leukemia, the exact cause of AML is
also unknown but some environmental factors are
linked including exposure to radiation and
benzene. Other causes are Antecedent hematologic
disorders, congenital disorders, familial
syndromes, prior exposure to chemotherapeutic
agents for another malignancy.
Symptoms:
-
anemia
-
bleeding
-
bruising
-
fever
-
persistent weakness
-
fatigue
-
aches in bones and joints
-
swollen lymph nodes
Treatments
-
chemotherapy
-
radiation therapy
-
bone marrow transplantation
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regarding your individual medical
and health care needs. Please
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